SINTEF – Norway

Stiftelsen Sintef ICT, The Instrumentation Department of the SINTEF ICT institute
Forskningsveien 1
0314 Oslo, Norway

d-LIVER Contact:

Frode Strisland
Senior Scientist
Tel: +47 22067360
E-mail: frode.strisland(at)sintef.no
Website: www.sintef.no

 

The SINTEF Group is a multidisciplinary, non-profit research organization based in Norway. With 2100 employees, SINTEF is the largest independent research organization in Scandinavia. SINTEF offers research-based knowledge and related services to customers in industry, venture companies and the public sector world-wide. More than 90 percent of SINTEF earnings come from contracts for industry, the public sector, and from project grants from the Research Council of Norway.

SINTEF is organized into seven research divisions, one of which is SINTEF Information and Communication Technology (ICT). d-LIVER will involve SINTEF ICT, which is a 300 employee institute covering R&D in the fields of microtechnology, instrumentation, communication and informatics. The Instrumentation Department within SINTEF ICT (18 people) creates integrated electronics and miniaturized instrumentation systems. The group has broad competence that encompasses integrated circuit designs, signal processing, instrumentation, and communication. Health-related sensor and instrumentation systems constitutes one of two research directions in the department. Projects are based on a holistic research approach that focuses on patient needs, and incorporates clinical care processes, how sensors and instrumentation can be designed and used to capture clinical information, how this is shared effectively in a health information system, and finally, how the total patient information is assembled and can be used to clinically understand the patient with assistance from multi-parameter decision support systems.

SINTEF contributes to d-LIVER as leader for WP2 System design and medical device regulatory requirements, be responsible for the wearable physical sensors for liver patient status monitoring in WP3 Sensor Development, and contributes to the integration of hardware into an instrument platform for the d-LIVER devices that will be built for technology validation.

SINTEF is currently carrying out a $3.6 million telemedicine project, MEDICOM, which is financed by US Congress and directed by US Army/TATRC (Telemedicine and Advanced Technology Research Center). In MEDICOM, a patient physiological monitoring system for physical rehabilitation processes in home environments will be developed. The d-LIVER wearable sensor system will be based on this work. SINTEF will also be responsible for physiological data acquisition and interpretation in a new FP7 human-cognitive robot for gait rehabilitation project (CORBYS, start Feb 2011). SINTEF has developed lab-on-a-chip in vitro diagnostic instrumentation in previous projects. SINTEF was involved in the FP6 IP project SmartHEALTH, being responsible for developing an instrument for complete sample processing from sample to complete nucleic acid amplification and detection using the qPCR process within a lab-on-chip cartridge.  In addition, SINTEF coordinated and had an instrument and hardware integration role the related completed lab-on-chip STREP project MicroActive (Automatic Detection of Disease Related Molecular Cell Activity).  SINTEF also has experience from numerous projects in the past within scenario driven system design methodologies for software and hardware systems.

Dr Frode Strisland received his MSc degree (1994) and dr.ing (~PhD) degree (1998) in experimental physics from the Norwegian University of Science and Technology. Since then he has been working at SINTEF presently as Senior Scientist. His research is related to sensor and electronics packaging, and integration of electronics and sensors into compact instrumentation systems. He is the project manager of the MEDICOM project developing wearable physiological measurement system for medical rehabilitation. He was SINTEF’s technical responsible within the SmartHEALTH project, and will be for the FP7 IP project (CORBYS, start Feb 2011). He has project management education from the Norwegian School of Management, and has been the project manager of several biomedical and wearable electronics projects within SINTEF.

Stig Morten Borch: MSc. Biochemistry University of Oslo in 1979 and has nearly 30 years experience in R&D management within diagnostics industry (Nycomed Imaging, Nycomed Pharma and Axis-Shield PoC), the last 15 years as R&D director for the development of new in vitro diagnostic platforms. He is key inventor of the successful “point of care” in vitro diagnostic platforms; NycoCard® and Afinion®. Further he had the overall responsibility for the technical development of these platforms until established “work like” and “look like” prototypes. Since August 2007 he has be associated with SINTEF ICT as Senior Research Scientist involved in a variety of projects and focused on system integration, microfluidics for lab-on-a-chip applications, reagent storage in medical devices, biofunctionalisation of surfaces and new sensor development. He is a key inventor in six patents/applications on which three different in vitro diagnostic platform principles are based.