IMM – Germany

Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. FhG-ICT-IMM Logo300dpi
ICT-IMM (IMM)

Carl-Zeiss Str. 18 – 20
55129 Mainz, Germany

d-LIVER Contact:

Baßler2012Michael Bassler
Senior Scientist – Microfluidic Analysis Systems Department
Tel: + 49 613 1990131
E-mail: michael.bassler(at)imm.fraunhofer.de

Website: www.imm.fraunhofer.de

 

The Fraunhofer-Gesellschaft promotes and undertakes applied research in an international context, of direct utility to private and public enterprise and of wide benefit to society as a whole. By developing technological innovations and novel systems solutions for their customers, the Fraunhofer Institutes help to reinforce the competitive strength of the economy in their region, throughout Germany and in Europe. Their research activities are aimed at promoting the economic development of our industrial society, with particular regard for social welfare and environmental compatibility. The Fraunhofer ICT-IMM is part of the Fraunhofer-Gesellschaft with currently 67 institutes. Our scientists carry out research and development within the key competences Decentralized and Mobile Energy Technology, Continuous Chemical Engineering, Medical Probes and Technical Sensors, Microfluidic Analysis Systems and Nanoparticle Technologies. The knowledge we gain and the developments which evolve from these fields are applied in the business areas Energy and Environment; Chemistry, Process Technology and Aviation and Aerospace; Biomedical Analytics and Diagnostics and Security as well as Industrial Analytics Applications. We build a bridge between basic research and application, because the developments pass through the institute beginning from the idea to the basic and application-oriented research to the point of their realization into custom built and market-ready results. We are not just developing our applications for and with industry but we are also interested in further developing them in a project-oriented manner. We work together with industrial enterprises as well as with research institutions and universities to answer future questions in projects which are co-financed by the national government, the federal states and the European Union.

Based on a platform for rapid lab-on-a-chip development Fraunhofer ICT-IMM’s expertise in fluidics especially comprises: chip-based analytics; micro-fluidic systems for diagnostics and sample preparation; chip systems for electrophoresis, DNA/RNA amplification, bio-particle concentration and biosensors for environmental monitoring and foodstuff analysis as well as modelling and simulation. The project MODULAB (Modulares Labor aus mikrotechnisch gefertigten Bausteinen; BMBF/16SV1355) established a platform for rapid chip development. Within the Q-LAB project (BMBF-V3BIO015, FKZ16SV3321, Automated Miniaturised Molecular Diagnostic System for Nucleic Acids Analysis from Sputum) the former IMM was responsible for the development of the microfluidic system for the analysis of nucleic acids of pathogens within sputum samples. In CD-MEDICS (ICT- 216031; Development of an integrated system comprising polymer chip, control device, and data processing for the multiparametric diagnosis of celiac disease) Fraunhofer ICT-IMM deals with aspects of hardware integration and sensor realisation. MICROFLUID (ICT-224205) deals with the Micro-Fabrication of a polymeric Lab-on-a-chip by Ultrafast lasers with Integrated optical Detection. Main application area is the mycotoxin detection in animal feed. Within the REACTION (ICT-248590) project a fiber optical sensor, integrated in micro-needles for subcutaneous blood glucose level measurement of diabetes patients is developed.

The role in the project is microfluidic sample preparation, sensor detection units and packaging. This is supplemented by expertise in optical detection and sensing technologies. A number of previous projects have created a sound basis for the tasks to be performed in this project.

Key personnel involved

Dr. Michael Bassler studied physics at the Friedrich-Alexander University, Institute of Applied Physics, Erlangen, Germany, where he received the doctoral degree in 2000 for his work on electrical and optical properties of MOS structures on silicon carbide. From 2001 to 2005 he served as project manager and director of sales at Thermosensorik GmbH, Erlangen, Germany, focussing on the development and marketing of industrial applications for state-of-the-art infrared camera systems. From 2005 to 2008 he joined the optofluidic group at Palo Alto Research Center (PARC), Palo Alto, California, as a principal investigator for the development of Lab-on-a-Chip systems with integrated optical components. He re-joined Thermosensorik GmbH in 2008 and served as director for R&D moving innovative ideas into industrial solutions. In 2009 he took the position of a scientist in the fluidic and simulation department at IMM, Mainz, Germany. He was awarded with a Starting Grant from the European Research Council in 2010 to establish as a principal investigator a new research group in the field of on-chip cytometry.

Dr. Klaus Stefan Drese studied physics at the Julius Maximilian University in Würzburg and at the State University of New York at Stony Brook. He received his PhD in theoretical physics in the field of time-dependent quantum mechanics at the Phillips University in Marburg. He joined the simulation group of IMM in 1998, became head of the Fluidics and Simulation Department in early 2004 and now, since March 2007, is Scientific Director. The responsibilities of Dr. Drese cover the entire development of micro- and bio-fluidic systems including simulation, silicon and thin film technology, laser material processing and optical sensors, mechanical micro machining as well as measuring technologies.

Dr. Tobias Schunck studied biology at the University of Rostock and Karlsruhe and obtained his degree in 2007. During his Diploma thesis at the Max Rubner Institut he worked in the field of  the prevention of mycotoxins in food. In 2011 he received his doctoral degree in protein expression and biochemical characterization at the Institute for Microbiology, University of Karlsruhe. He joined the Microfluidics and Analytics Department at IMM in September 2011. His work is focused on the development of microchip-based systems for bioanalytics and diagnostics.